French tarragon (Artemisia dracunculus) essential oil is dominated by estragole (methyl chavicol), which typically constitutes 70-80% of the oil and is responsible for its anise-like aroma and antispasmodic properties.^[1] However, estragole is classified as a genotoxic hepatocarcinogen in rodent studies; it forms reactive DNA adducts following metabolic bioactivation, raising safety concerns for chronic or high-dose exposure.^[2]